Lab-on-a-Foil with Roll-to-Roll
Lab-on-a-Foil represents a leap forward in microfluidics by using flexible films to produce thin, versatile lab-on-chip devices. The method combines traditional and novel fabrication techniques and offers a wide choice of materials. At its core, it promises low-cost, high-volume production of disposable chips suitable for a wide range of applications such as diagnostics and environmental analysis.
UV-Nanoimprint Lithography
UV-Nanoimprint Lithography (UV-NIL) resist properties can be precisely tailored through modifications in the photo polymer formulation, allowing for customization of wettability, biofunctionalization, optical, and mechanical characteristics to suit specific applications.
Extrusion Coating
Roll-to-Roll Extrusion Coating (R2R-EC) offers a swift and effective way to apply coatings on microfluidic chips. It is compatible with familiar thermoplastic polymers, leveraging their well-known properties akin to those utilized in injection molding.
Efficient processes minimize production costs, making it a budget-friendly option for large-scale projects.
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Cost-Effective
R2R can be used with a variety of flexible substrates, including polymers and flexible electronics, allowing for versatile design options.
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Flexible Material
R2R processes are highly scalable, allowing for the cost-effective mass production of microfluidic devices.
Scalability
The continuous nature of R2R fabrication enables high-throughput production.
High Throughput
Key Benefits of R2R Replication
Considerations for Choosing R2R for Microfluidic Chip Production
R2R-EC is compatible with common thermoplastic polymers such as PS, COP/COC, PMMA, PC, and PET, while R2R UV-NIL works with photopolymers on flexible substrates like PET, PC, and PS. Selecting the right material is essential for ensuring quality and functionality of the microstructures.
Material Specification
Both methods are efficient for medium to mass production volumes ranging from 100k to 100 million. This means they may not be the most cost-effective solution for small-scale production.
Production Volume
Changes in design or process parameters can require additional setup and optimization.
Design and Process
Reference Cases
We've selectively partnered with industry leaders known for their expertise in Roll-to-Roll processes.
Why choose MIH?
Contact us to discuss your microfluidic project requirements and objectives.
Consultation
Partner Match
We connect you with the roll-to-roll replication experts from our network.
We oversee the entire project, ensuring smooth coordination and timely delivery.
Project Management
Coloured area indicates the method's ideal chip production volume.
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