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Unlocking Microfluidic Innovation with Soft Lithography

Soft lithography is a versatile and cost-effective method for creating microfluidic devices. Utilizing elastomeric stamps, molds, or masks—typically made from polydimethylsiloxane (PDMS)—this technique transfers intricate patterns onto various substrates.

Lab Fabrication

Soft lithography with PDMS provides a gateway to microfabrication in your own lab. Known for its simplicity and precision, this method allows researchers to create detailed microfluidic devices without the need for extensive industrial infrastructure. It enables rapid prototyping and refinement of designs before they are deployed on a larger scale.

Foto of scientist in laboratory checking microfluidic chip features manufactured with soft lithography - foto by joanneum research, member of microlfuidics innovation hub.

Soft Lithography

Discover the versatility of soft lithography for innovative microfluidic designs. Our rapid prototyping services transform your theoretical models into tangible prototypes, increasing the speed and accuracy of your development process.

Rapid Prototyping Service

Microfluidic chip made by soft lithography by joanneum research, a microlfuidic innovation hub member.

Achieves features with micrometer-scale resolution, suitable for intricate microfluidic designs.

High precision icon to demonstrate feature resolution in soft lithography manufacturing technique for  microfluidic chip replication service at microfluidics innovation hub.

High Precision

Enables quick turnaround from design to prototype, accelerating the development cycle.

Rapid Prototyping graphic to showcase speed of prototyping for soft lithography technique for prototyping lab-on-chips at microfluidic innovatin hub.

Rapid Prototyping

PDMS, the most commonly used material in soft lithography, is biocompatible, making it ideal for biomedical applications.

Biocompatibility icon to showcase good material selection with PDMS for soft lithograpy replication for microfluidic chips.

Biocompatibility

Key Benefits of Soft-Lithography

Download Specs
Soft Lithography microfluidic chip manufacturing method specification sheet - mock-up by MicrofluidicsInnovationHub.

Considerations for Choosing Soft Lithography for Microfluidic Chip Production

The quality of the master mold directly impacts the precision and reproducibility of the final product. Invest in high-quality master molds for consistent results.

Master Mold Quality

Delve beyond PDMS to explore a variety of materials soft lithography can work with, including novel photoresists and biocompatible polymers. Evaluate how material choices affect your device's functionality, especially in terms of chemical compatibility, optical clarity, and mechanical properties. Consider the interaction between the substrate and the elastomeric mold to prevent adhesion issues or deformation.

Material Selection and Compatibility

Initially cost-effective for prototype and small batch production, soft lithography's economic advantage may diminish as volume increases, primarily due to the labor-intensive nature of mold creation and casting. Carefully assess the scalability of soft lithography for your project, considering factors like mold reuse, automation potential, and the incremental cost of scaling up production.

Scalability and Production Economics

Reference Cases

We bring your microfluidic design to life.

Ready to prototype?

Contact us to discuss your microfluidic project requirements and objectives.

Consultation

Partner Match

We connect you with the soft lithography experts from our network.

We oversee the entire project, ensuring smooth coordination and timely delivery.

Project Management

Image by MicrofluidsInnovationHub, showcasing the Production Volume capabilities of soft lithography for microfluidic chip manufacturing.

Coloured area indicates the method's ideal chip production volume.

10

1000

10 000

100 000

100 000 000 +

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